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Isotretinoin
Isotretinoin
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6.5
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RateADrug users have reported 9 Isotretinoin side effects and 3 Isotretinoin benefits.
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Warnings
Isotretinoin is the generic name and it is manufactured and sold under the brand names: Accutane, Sotret, Claravis, Amnesteem. It is used in the treatment of extreme cases of nodular acne where other forms of treatment including antibiotics have failed.
It belongs to a group of medications referred to as retinoids. It functions by inhibiting the production of varopis natural elements that can give rise to pimples.
The inactive ingredients of isotretinoin are beeswax, butylated hydroxyanisole, edetate disodium.
It is available in tablet form and needs to be administered orally.
Common Uses:
Isotrentinoin is used in the treatment of extreme cases of recalcitrant nodular acne.
Off Label Uses:
Used as a chemotherapeutic agent in treating certain types of cancer.
Side Effects:
Signs of psychological changes or depression like:
Sadness.
Hopelessness.
Feelings of guilt and worthlessness.
Lack of interest in activities that one used to engage in previously.
Fatigue.
Difficulty concentrating.
Insomnia.
Loss of appetite.
Suicidal thoughts.
Restlessness.
Hypersensitivity.
Impulsive reactions.
Hallucinations.
Delusions.
Signs of increased blood pressure within the cranium, such as:
Headaches.
Nausea.
Vomiting.
Vision changes.
Pancreatitis.
Tinnitus or ringing sound in the ears.
Hearing loss.
Yellowness to eyes and skin.
Abdominal pain especially in the upper-right corner.
Increased liver enzymes.
Ulcerative colitis.
Broken bones.
Osteoporosis.
Vision changes.
Alterations in blood sugar levels.
Seizures.
Stroke.
Allergic reactions.
Swelling of the lips, mouth, and throat.
Breathing problems.
Wheezing.
Cautions / Warnings:
Not recommended in pregnant women.
Available only on registering with the iPLEDGE program.
Patients with a family history of depression, psychosis, etc., need to consult their physician prior to taking this medication.
When administered with tetracycline, it can cause pseudotumor cerebri, where there could be high pressure inside the cranium.
Medication to be discontinued if vision changes occur and also one should avoid driving.
Strongly advised against donating blood while on this medication.
Drug Interactions:
Antibiotics like:
Doxycycline.
Minocycline.
Tetracycline.
Tigecycline.
Corticosteroids like:
Betamethasone.
Cortisone.
Dexamethasone.
Fludrocortisone.
Hydrocortisone.
Methylprednisolone.
Prednisolone.
Prednisone.
Triamcinolone.
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Lichen sclerosus
Liver Disorder
Lou Gehrig's Disease
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Medicine / Fluid Absorption
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Meniere's Disease & Vertigo
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Migraine
Mild splenomegaly
Motion Sickness
Mouth & Gum Disorder
MRSA
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Myasthenia Gravis
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Rickets
Rosacea
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Sjogren's Syndrome / Dry Mouth
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Purple foods such as concord grapes, blueberries, plums, pomegranates, acai berries, red wine, and even eggplants are very high in antioxidants. Purple foods have been shown to protect your heart and vision, promote mental focus, and increase longevity. Research has indicated that purple foods may even be used to prevent or cure cancer.
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Isotretinoin Comments
14 Nov 2021
FDA Approved medicines without prescription Kindly place your orders here with heavy discounts available, Call and text 1(775)-773-5306 Whatspp only :- +1(775)-773-5306 are Ambien, Valium, Xanax, Klonopin, Tramadol, and Soma. We have available stocks for Oxycontin, Hydrocodone, Adderall and Ativan etc. Deliver the package in 2-3 days after placing the order.' Don't think just place your order now by email or by sending SMS. Also, if you need a picture of medicines, place your order. Do let us know because we believe in Customer Satisfaction. We do overnight shipping also on request. Feel free to contact us for any queries. Regards, Health Care Call and text 1(775)-773-5306 Whatspp only :- +1(775)-773-5306, You can send a small note to: peterkings2014 @ gmail. com.
—Posted by Anonymous
17 Feb 2012
Lost my sex drive almost completely, and I'm only 3 months in. Made my skin very dry, especially on the backs of my hands and my upper arms. My lips and nostrils were very dry until I discovered Aquaphor. Sexually, though, I am most concerned.
—Posted by Chelsea S
04 Apr 2011
Dear Matt, I also experienced a similar and drastic decrease in sex drive coupled with inability to achieve orgasm, decreased sensation and pleasure, pain, less lubrication during masturbating. Would youplease tell me if your similar side effects vanished after you stopped taking the medicine? I m really worried if taking this medicine has ruined my sex life. Please reply. Many thanks. Best wishes, Indira
—Posted by Indira
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14 Nov 2021
FDA Approved medicines without prescription Kindly place your orders here with heavy discounts available, Call and text 1(775)-773-5306 Whatspp only :- +1(775)-773-5306 are Ambien, Valium, Xanax, Klonopin, Tramadol, and Soma. We have available stocks for Oxycontin, Hydrocodone, Adderall and Ativan etc. Deliver the package in 2-3 days after placing the order.' Don't think just place your order now by email or by sending SMS. Also, if you need a picture of medicines, place your order. Do let us know because we believe in Customer Satisfaction. We do overnight shipping also on request. Feel free to contact us for any queries. Regards, Health Care Call and text 1(775)-773-5306 Whatspp only :- +1(775)-773-5306, You can send a small note to: peterkings2014 @ gmail. com.
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17 Feb 2012
Lost my sex drive almost completely, and I'm only 3 months in. Made my skin very dry, especially on the backs of my hands and my upper arms. My lips and nostrils were very dry until I discovered Aquaphor. Sexually, though, I am most concerned.
—Posted by Chelsea S
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18 Aug 2010
Isotretinoin is a nightmare, if you are thinking of taking it DONT! 3 years after go off the drug my bones still creak every time i climb a step, my liver is still recovering and more recently I have been diagnosed with Hyperthyroidism. I was 26 when I started the medication; I had lived with acne most of my live but just could not bear it any more as I felt embarrassed going to work or making presentations. I was place on isotreinoin but only stay on it for 3 months before stopping, my skin was literally falling off, I could not work as I was constantly depressed and tired, every night (up till today) I still have chest pains. At that time I thought acne was the worse thing that could happen to me, now 3 years later and still living with the effects of Isotretinoin, I wish I had my health and my acne back. Please before taking this drug, I beg you to reconsider; it may be the MISTAKE OF YOUR LIFE as it was for me.
—Posted by David
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04 Jun 2009
I've been taking this medication for almost 2 years now. It is absolutely great in controlling my acne and I haven't seen improvements like this with anything else. It is extremely effective and works almost immediately. I wouldn't know what to do without it. Apart from the dry lips and skin, and frequent thirst, the medicine does induce depression in me, to the extent of people asking if something is wrong. It's strange in how it alters your mood at times and I see a distinct difference when I forget to take the dosage constantly over a week. I am very aware of my mood swings and do my best to overcome them, knowing that they have been induced by the drug.
—Posted by 28male
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12 May 2009
This is my second round of Isotretinoin. The first time the results lasted for about 3 1/2 years before I started having bouts of cystic acne again (definitely related to stress). The first time I was on it I had a lot of joint and muscle pain but I have not experienced that this time around. This time in addition to the normal dry skin, lips, and increased thirst, I have dry eyes and a dry nose that bleeds frequently if I do not use the nasal gel to moisten it. These side effects are well worth the results that come with it. As my acne got worse, so did the amount of sebum produced on my scalp. I would take a shower in the morning and by the afternoon my hair was greasy. That has also completely stopped. As far as the mood effects and energy levels, who knows if it is the drug or not. I am in vet school and my stress level is very high to begin with. Am I more "depressed"? Sure, but I'm 1400 miles from home in a place I don't really like with a lot of pressure on me at all times. That alone can cause lack of energy, sleep disturbances, etc. I hesitate to blame it all on a medication (which I think a lot of people do) when most of it would be here with or without the meds. I am far from suicidal or psycosis. I think as long as you can live with the side effects (as long as they are not the serious ones) the medication's results are well worth putting up with a few months of minor discomfort.
—Posted by Jennifer
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