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Ortho Tri-Cyclen

Ethinyl estradiol + Norgestimate

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Satisfaction

6.4

6 Effectiveness

5.5 Side Effects

5.9 Holistic Benefits

RateADrug users have reported 8 Ortho Tri-Cyclen side effects and 2 Ortho Tri-Cyclen benefits.

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Treatment Information

Description | Uses & Side Effects | Warnings

Ortho Tri-Cyclen is a combination oral contraceptive containing the progestational compound norgestimate and the estrogenic compound ethinyl estradiol.

Each white tablet contains progestational compound, norgestimate, oxime, and estrogenic compound, and ethinyl estradiol. Inactive ingredients include lactose, magnesium stearate, and pregelatinized corn starch.

Each light blue tablet contains progestational compound norgestimate, estrogenic compound, and ethinyl estradiol. Inactive ingredients include FD & C Blue No. 2 Aluminum Lake, lactose, magnesium stearate, and pregelatinized corn starch.

Each blue tablet contains progestational compound norgestimate, estrogenic compound, and ethinyl estradiol. Inactive ingredients include FD & C Blue No. 2 Aluminum Lake, lactose, magnesium stearate, and pregelatinized corn starch.

Each green tablet contains only inert ingredients, as follows: D & C Yellow No. 10 Aluminum Lake, FD & C Blue No. 2 Aluminum Lake, lactose, magnesium stearate, microcrystalline cellulose and pregelatinized corn starch.

Common Uses:

Ortho Tri-Cyclen tablets are used for prevention of pregnancy in women who elect to use oral contraceptives as a method of contraception.

Ortho Tri-Cyclen is also used in the treatment of moderate acne vulgaris in females at least 15 years of age, who have no known contraindications to oral contraceptive therapy and have achieved menarche. This medication should be used for the treatment of acne only if the patient desires an oral contraceptive for birth control.

Off Label Uses:

At this time, off-label Ortho Tri-Cyclen Lo uses include treatment for the following conditions:

Acne
Heavy menstrual bleeding
Painful menstrual periods
Irregular menstrual periods
Premenstrual dysphoric disorder (PMDD)
Various other problems, such as polycystic ovary syndrome

Side Effects:
Some of these common bothersome (but not usually dangerous) side effects include:

Headaches (although birth control pills can improve headaches in some women)
Breakthrough bleeding and spotting between periods (especially for the first few cycles)
Nausea and vomiting
Changes in your eyes that make it more difficult to wear contact lenses
Bloating
Breast tenderness or other breast changes, such as swelling
Changes in sex drive (often a decrease, rather than an increase).

Women are often concerned about weight gain due to birth control pills, but recent research suggests that birth control pills probably do not cause weight gain for most women.

Some side effects with Ortho Tri-Cyclen, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:

Signs of a stroke, such as:

Vision or speech changes
Weakness or numbness in an arm or leg
Severe headache

Signs of liver damage, such as:

Yellow eyes or skin (jaundice)
Dark urine
Upper-right abdominal (stomach) pain

Depression or other emotional changes
Migraines (or changes in your migraines, if you have had them before)
Breast lumps
Signs of a blood clot in the leg, such as:

Pain in the calf
Leg cramps
Leg or foot swelling

Signs of a blood clot in the lung, such as:

Shortness of breath
Sharp chest pain
Coughing up blood

Chest pain or heaviness, which may be signs of a heart attack
Sudden loss of vision or vision changes, which can be a sign of a blood clot in the eye
Heavy vaginal bleeding between periods (light bleeding or spotting is normal)
High blood pressure (hypertension)
High cholesterol
Signs of an allergic reaction, such as:

Unexplained rash
Hives
Itching
Unexplained swelling
Wheezing
Difficulty breathing or swallowing.

Cautions / Warnings:

Warnings and precautions to be aware of prior to using Ortho Tri-Cyclen Lo include the following:

Combined oral contraceptives, including Ortho Tri-Cyclen Lo, increase the risk of blood clots, strokes, and heart attacks. These risks are quite small for healthy, young nonsmokers. However, make sure to tell your healthcare provider if you have ever had a blood clot, stroke, heart attack, or chest pain. Smoking cigarettes greatly increases the risk of serious Ortho Tri-Cyclen Lo side effects. This risk is particularly high for smokers over the age of 35.

Hormonal contraceptives, including Ortho Tri-Cyclen Lo, can increase your blood pressure. This can be a problem if you already have high blood pressure.

Ortho Tri-Cyclen Lo does not protect against HIV, AIDS, or other sexually transmitted diseases (STDs). In many cases, it is advisable to use condoms in addition to Ortho Tri-Cyclen Lo.

Ortho Tri-Cyclen Lo can interact with a number of different medications.

Combined oral contraceptives may slightly increase the risk of breast cancer or cervical cancer, although this is an unresolved and controversial issue. However, combined oral contraceptives seem to help protect women against ovarian and uterine cancer.

Oral contraceptives increase the risk of benign (noncancerous) liver tumors. In rare cases, these tumors can rupture and cause serious problems.

Hormonal contraceptives such as Ortho Tri-Cyclen Lo may make gallbladder disease worse. If you have had a problem with your gallbladder, Ortho Tri-Cyclen Lo may not be the best contraceptive method for you.

Ortho Tri-Cyclen Lo may increase blood sugar, particularly in women with diabetes. Your healthcare provider may need to monitor you more closely. Let your healthcare provider know if you have any sudden vision changes while taking the drug, as this may be a sign of a blood clot in the eyes (a possible side effect of Ortho Tri-Cyclen Lo and other hormonal contraceptives).

Ortho Tri-Cyclen Lo can change your menstrual bleeding patterns. Some women have breakthrough bleeding (bleeding between periods), while others may not have a period at all. It is normal to have shorter and lighter periods while using the drug. However, if you notice any unusual changes in your bleeding patterns, let your healthcare provider know. If you miss a period, you should make sure you are not pregnant.

Ortho Tri-Cyclen Lo can affect your cholesterol. Your healthcare provider may need to check your cholesterol levels after you start the drug, especially if you already have high cholesterol.

Sometimes, hormonal contraceptives may make depression worse. Let your healthcare provider know if you develop new or worsening depression symptoms while taking Ortho Tri-Cyclen Lo.

Occasionally, Ortho Tri-Cyclen Lo (as well as any other hormonal contraceptive) can cause eye changes that make it more difficult to wear contact lenses.

Ortho Tri-Cyclen Lo is considered a pregnancy Category X medication. This means that it should not be used during pregnancy.

Contraceptive hormones, such as the ones in Ortho Tri-Cyclen Lo, pass through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Ortho Tri-Cyclen Lo and Breastfeeding). Combined hormonal contraceptives are usually not recommended for breastfeeding women.

Drug Interactions:
Ortho Tri-Cyclen(norgestimate/ethinyl estradiol) can potentially interact with numerous other medicines. Many of these interactions can be severe enough to cause accidental pregnancy, and a backup method of birth control may be recommended.

If you are ever unsure what to do about an Ortho Tri-Cyclen drug interaction, be sure to use backup birth control until you can speak with your healthcare provider. Some of the medicines that may lead to Ortho Tri-Cyclen drug interactions include:

Aminoglutethimide (Cytadren®)
Antibiotics
Aprepitant (Emend®)
Atorvastatin (Lipitor®)
Barbiturate medications, such as:

Amobarbital (Amytal®)
Butalbital (Fioricet®, Fiorinal®)
Pentobarbital (Nembutal®)
Phenobarbital (Luminal®)
Secobarbital (Seconal®)

Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
Many seizure medications, such as:

Carbamazepine (Carbatrol®, Epitol®, Equetro™, Tegretol®)
Felbamate (Felbatol®)
Lamotrigine (Lamictal®)
Oxcarbazepine (Trileptal®)
Phenytoin (Dilantin®, Phenytek®)
Topiramate (Topamax®)

Modafinil (Provigil®)
Protease inhibitors, such as:

Amprenavir (Agenerase®)
Atazanavir (Reyataz®)
Fosamprenavir (Lexiva®)
Indinavir (Crixivan®)
Nelfinavir (Viracept®)
Ritonavir (Norvir®)

Selegiline (Eldepryl®, Emsam®, Zelapar®)
St. John's wort (Hypericum perforatum)
Theophylline (Uniphyl®, Theocron®, TheoCap®, Theo-24®, Elixophyllin®)

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Brands	Effectiveness	Holistic Benefits	Side Effects	Number of Ratings
NuvaRing	7.9	6.29	3.85	86
Yaz	6.6	5.83	4	159
Loestrin	6.58	5.61	4.14	99
Yasmin	6.51	5.46	3.87	63
Ortho Tri-Cyclen	6.13	5.59	4.2	165

View All	About these Scores
	Choose a condition to compare treatments based on user feedback. You can sort by Effectiveness, Holistic Benefits or Side Effects RateADrug user scores, or the number of Ratings. Scores gain significance with the number of ratings, so please share your experiences - rate your drug! Close

Effectiveness of Ortho Tri-Cyclen by Condition

Click on a condition to view RateADrug.com users ratings

Birth Control

Acne

Hair Loss / Thinning

Hormone Imbalance

Ovarian Cysts

- - - - - - - - - - - - - - - - -

Effectiveness on "Birth Control"

About these Results
Out of 100% of people surveyed, these results show the distribution in percentages of how users rate the effectiveness of their medication. Click on the various conditions to see how the effectiveness ratings change. Close

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How effective is Ortho Tri-Cyclen?

Reported Changes in Health and Well-Being

Since taking Ortho Tri-Cyclen, RateADrug survey participants noticed these changes in their health:

Effect on:	Much Worse	Worse	No Change	Better	Much Better
Appetite	4.9%	12.6%	71.8%	8.7%	1.9%
Balance/Equilibrium	3%	3.9%	89.7%	1.5%	2%
Blood Pressure	1.5%	2.5%	94.5%	1.5%	0%
Breathing	1.5%	3%	92.6%	2%	1%
Confidence	2.9%	10.1%	78.3%	6.8%	1.9%
Coordination/Motor Skills	1%	1.5%	94.1%	3.4%	0%
Digestion	2.9%	4.9%	84.9%	5.4%	2%
Emotional Well-being	11%	18.2%	56%	12%	2.9%
Energy	2.4%	16.4%	71.5%	8.2%	1.4%
Eyesight	1.5%	3.4%	92.1%	3%	0%
Memory	2.9%	4.9%	89.8%	1.5%	1%
Mental Clarity	3.9%	11.2%	79.6%	3.4%	1.9%
Pain	4.9%	8.3%	78.9%	6.9%	1%
Patience	6.8%	14.1%	72.2%	5.4%	1.5%
Sexual Health	5.8%	8.2%	61.8%	19.3%	4.8%
Skin Complexion	4.3%	10.5%	49.8%	23.4%	12%
Sleep	2%	10.7%	81%	4.9%	1.5%
Stress Level	5.3%	18.8%	65.2%	7.2%	3.4%

About these Scores
Out of 100% of people surveyed, these results show the distribution in percentages of negative or positive changes in health and well-being experienced by users for all of the categories listed. Close

Commonly Reported Ortho Tri-Cyclen Side Effects

RateADrug survey participants experienced these commonly reported side effects:

Effect on:	None	Mild	Moderate	Strong	Severe
Acne	78.6%	10.7%	6.5%	2.4%	1.8%
Allergic Reaction	97.4%	1%	1.5%	0%	0%
Anxiety	66.7%	12.1%	9.1%	6.1%	6.1%
Blurred Vision	75.8%	12.1%	12.1%	0%	0%
Breast Tenderness	51.2%	26.4%	13.9%	6%	2.5%
Breathing Difficulties	93.9%	0%	6.1%	0%	0%
Change in Sex Drive	65.7%	13.7%	9.8%	5.4%	5.4%
Cold Symptoms	72.7%	15.2%	9.1%	3%	0%
Confusion	93.9%	3%	0%	3%	0%
Depression	68.1%	11.8%	8.3%	8.3%	3.4%
Diarrhea	78.8%	9.1%	9.1%	3%	0%
Dizziness	78.6%	10.4%	6.5%	2.5%	2%
Drowsiness	75.8%	9.1%	9.1%	6.1%	0%
Fatigue	70.2%	12.7%	8.3%	4.4%	4.4%
Fever	97%	3%	0%	0%	0%
Gas	81.8%	6.1%	12.1%	0%	0%
Headache	62.6%	16.7%	11.3%	6.9%	2.5%
High Blood Pressure	93.4%	3%	1.8%	0.6%	1.2%
Insomnia	84.8%	6.1%	3%	3%	3%
Irregular Bleeding	76.7%	11%	3.4%	2.7%	6.2%
Irregular Heartbeat	93.9%	3%	3%	0%	0%
Mood Swings	53.4%	15%	13.6%	11.7%	6.3%
Muscle Cramping	78.8%	9.1%	9.1%	3%	0%
Nausea	66.3%	17.3%	9.9%	4.5%	2%
Sensitivity to Light	90.9%	9.1%	0%	0%	0%
Sexual Dysfunction	84.8%	9.1%	6.1%	0%	0%
Stomach Ache	69.7%	21.2%	9.1%	0%	0%
Yeast Infection	84.3%	7.6%	3.5%	2%	2.5%

About these Scores
Out of 100% of people surveyed, these results show the distribution in percentages of the severity of side effects experienced by users. Scores gain significance with the number of ratings, so please share your experiences - rate your drug! Close

Less Commonly Reported Ortho Tri-Cyclen Side Effects

RateADrug survey participants experienced less commonly reported side effects:

Effect on:	None	Mild	Moderate	Strong	Severe
Abdominal Pain	59.5%	18.5%	10.4%	7.5%	4%
Anxiety	74.6%	10.7%	5.9%	4.7%	4.1%
Benign Liver Tumor	99.5%	0%	0%	0%	0.5%
Blurred Vision	92.3%	4.2%	1.2%	1.2%	1.2%
Breast Cancer	99%	0.5%	0%	0%	0.5%
Breathing Difficulties	92.8%	2.4%	3%	0%	1.8%
Cervical Cancer	96.9%	2.1%	0%	0%	1%
Change in Weight	56.9%	26.7%	7.9%	5.4%	3%
Chest Pain	89.8%	6.1%	2%	0.5%	1.5%
Diabetes	99%	0%	0%	0%	1%
Eye / Vision Problems	93.8%	4.1%	0.5%	1%	0.5%
Irregular Bleeding	70.6%	17.6%	9.8%	2%	0%
Irregular Periods (women)	80.4%	6.5%	6%	3%	4.2%
Numbing Sensation	93.4%	3.1%	1%	0.5%	2%
Pain in Limbs	88.4%	6.6%	2%	2%	1%
Reduced Libido	83.5%	12.7%	1.3%	0%	2.5%
Thrombosis (Blood Clotting)	96.9%	1%	0.5%	0%	1.5%
Vaginal Discharge	0%	100%	0%	0%	0%

About these Scores
Out of 100% of people surveyed, these results show the distribution in percentages of the severity of side effects experienced by users. Scores gain significance with the number of ratings, so please share your experiences - rate your drug! Close

Episodes since taking Ortho Tri-Cyclen

Since taking Ortho Tri-Cyclen Rate a Drug survey participants reported these episodes:

Auto Accident	0.8%
Hallucination	0.4%

Hospitalization	1.2%
Seizure	0.4%

About these Results
Out of 100% of people surveyed, these results show the percentage of users who have experienced any of these episodes while taking their medication. Close

How does your experience compare with other Ortho Tri-Cyclen users?

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User Comments about Ortho Tri-Cyclen

30 Jan 2012	A few days after I started using Ortho Tri-Cyclen I started having these reactions: Joing and muscle pain, headaches, and itching all over body. I've decided to quit taking them.. Don't want to have any more severe reactions to it. —Posted by Anonymous Respond Display Name: Email: (Required) Notify me of new comments Email me monthly survey results Sending... I agree to the Terms of Use
30 Jan 2012	A few days after I started using Ortho Tri-Cyclen I started having these reactions: Joing and muscle pain, headaches, and itching all over body. I've decided to quit taking them.. Don't want to have any more severe reactions to it. —Posted by Anonymous Respond Display Name: Email: (Required) Notify me of new comments Email me monthly survey results Sending... I agree to the Terms of Use
30 Jan 2012	A few days after I started using Ortho Tri-Cyclen I started having these reactions: Joing and muscle pain, headaches, and itching all over body. I've decided to quit taking them.. Don't want to have any more severe reactions to it. —Posted by Anonymous Respond Display Name: Email: (Required) Notify me of new comments Email me monthly survey results Sending... I agree to the Terms of Use
30 Jan 2012	A few days after I started using Ortho Tri-Cyclen I started having these reactions: Joing and muscle pain, headaches, and itching all over body. I've decided to quit taking them.. Don't want to have any more severe reactions to it. —Posted by Anonymous Respond Display Name: Email: (Required) Notify me of new comments Email me monthly survey results Sending... I agree to the Terms of Use
27 Sep 2011	Everything was fine for the first 3 months and then the last couple weeks I experianced, costipation, diarriha, hard of breathing, Hives. —Posted by dissapointed Respond Display Name: Email: (Required) Notify me of new comments Email me monthly survey results Sending... I agree to the Terms of Use