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Tamoxifen Citrate
Tamoxifen Citrate
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User Ratings
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5.8
2.5
Effectiveness
6.1
Side Effects
2.9
Holistic Benefits
RateADrug users have reported 11 Tamoxifen Citrate side effects and 2 Tamoxifen Citrate benefits.
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Description
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Uses & Side Effects
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Warnings
Tamoxifen is a nonsteroidal antiestrogen, which is administered orally and is part of a set of medications referred to as SERMs or selective estrogen receptor modulators. These have both estrogenic and anti-estrogenic effects. Tamoxifen has anti-estrogenic effects on the breasts and has estrogen-like effects on bones, working to strengthen them.
The inactive ingredients of tamoxifen citrat include carboxymethylcellulose calcium, magnesium stearate, mannitol and starch. Tamoxifen citrate is the active ingredient and it is available in 10 mg and 20 mg tablets.
Tamoxifen is used in the treatment of metastatic breast cancer in women and men and as a form of adjuvant treatment of breast cancer. It also decreases the risk of breast cancer in high risk women who are at a higher risk of developing breast cancer.
Common Uses:
Treatment of metastatic breast cancer in both women and men.
Alternative treatment to surgical removal of both ovaries and radiation treatment of the ovaries in postmenopausal women with metastatic breast cancer.
Minimizes the risk of ductal carcinoma in situ (DCIS)in women, post surgery and/or radiation treatment.
Decreases the occurrance of breast cancer in women that are at a high risk of developing carcinoma of the breast.
Off Label Uses:
Treatment of breast pain or mastalgia in women.
Side Effects:
Anemia.
Back pain.
Bone pain.
Chest pain.
Depression.
Diarrhea.
Difficulty breathing.
Fatigue.
Hair loss.
Headaches.
Heartburn or indigestion.
High blood pressure.
High cholesterol.
Hot flashes.
Infections.
Irregular menstrual periods.
Lack of sleep or insomnia.
Mood swings.
Muscle pain.
Nausea.
Osteoporosis.
Ovarian cysts.
Skin changes.
Vaginal bleeding.
Vaginal discharge.
Water retention.
Weight loss.
Cautions / Warnings:
Blood clots.
Strokes.
Uterine cancer.
Not recommended for people with bone metastases as it increases the calcium levels.
Not recommended for women with uterine cancer and ovarian conditions like ovarian cysts, fibroids, and endometriosis.
Not recommended in people with existing liver conditions like liver cancer, cirrhosis, and hepatitis.
Eye conditions include cataracts, vision changes, and other problems.
Not recommended for pregnant women and nursing mothers.
Drug Interactions:
Aminoglutethimide or Cytadren.
Anastrozole or Arimidex.
Anticonvulsants like carbamazepines like Epitol, Equetro, Tegretol, and Tegretol XR.
Bromocriptine or Parlodel.
Fosphenytoin or Cerebyx.
Oxcarbazepine or Trileptal.
Phenobarbital or Luminal.
Phenytoin or Dilantin.
Phenytek.
Primidone or Mysoline.
Chemotherapy medications like, estrogens or other hormone replacement therapy.
Letrozole or Femara.
Oral contraceptives or birth control pills.
Rifamycin antibiotics, including rifabutin or Mycobutin, rifapentine or Priftin.
Warfarin or Coumadin.
Jantoven.
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Try adding more purple to your diet!
Purple foods such as concord grapes, blueberries, plums, pomegranates, acai berries, red wine, and even eggplants are very high in antioxidants. Purple foods have been shown to protect your heart and vision, promote mental focus, and increase longevity. Research has indicated that purple foods may even be used to prevent or cure cancer.
- Mark
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Tamoxifen Citrate Comments
10 May 2016
just started a week ago and so far so good.
—Posted by Joseph
05 Jan 2013
I had a double mastectomy in November, 2011 at the age of 44 and went through chemo for five months (which pushed me in to early menopause) before starting Tamoxifen in June, 2012. Since starting Tamoxifen I have experienced severe night sweats and moderate hot flashes. Since October, 2012 I have suffered from Lichens Sclerosus, which was just diagnosed in January 2013. I have suffered severe vaginal dryness, due to lack of estrogen, since I have been on Tamoxifen.
—Posted by Margie1967
16 Dec 2012
since I started taking tamox I have noticed that i have more increased dreaming.Sometimes i cant tell the difference in reality and my dreams.My hot flashes have increased.
—Posted by Anonymous
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10 May 2016
just started a week ago and so far so good.
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05 Jan 2013
I had a double mastectomy in November, 2011 at the age of 44 and went through chemo for five months (which pushed me in to early menopause) before starting Tamoxifen in June, 2012. Since starting Tamoxifen I have experienced severe night sweats and moderate hot flashes. Since October, 2012 I have suffered from Lichens Sclerosus, which was just diagnosed in January 2013. I have suffered severe vaginal dryness, due to lack of estrogen, since I have been on Tamoxifen.
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since I started taking tamox I have noticed that i have more increased dreaming.Sometimes i cant tell the difference in reality and my dreams.My hot flashes have increased.
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22 Aug 2011
have had little or no discomfort while taking this medication. i do worry, however, about the long term side effects but i will not now about that for a while....
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26 Jan 2011
I have been on it for seven months and have hot flashes every night. I wake up every 2hours my joints are soar anytime I am not moving for more than one hour. I have lost most of my sex drive and orgasms have gone away. I seem to get bladder infections more easily. Have 4more years to go. Not sure if I am going to continue since some of the studies show only about taking it not. Not taking it. I'm only 49 and want a good quality of life now. Studies show that the tamoxifen shuts receptors off and they will not come back on. Not good if you want a sex life.
—Posted by Anonymous
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