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Amprenavir

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3.7 Effectiveness

2.3 Side Effects

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Description | Uses & Side Effects | Warnings

The generic name of this medication is amprenavir and the brand name is Agenerase.

The active ingredient of this medication is Amprenavir.

Agenerase capsules is manufactured by Glaxo SmithKline Pharmaceuticals.

This medication is used in treating HIV infection and it is administered in combination with other drugs.

Common Uses:

This medication is used in treating HIV infection and it is administered in combination with other drugs.

Off Label Uses:

None noted currently.

Side Effects:
Diarrhea/loose stools;
Headache;
Nausea;
Numbness or tingling around the mouth and in the hands and feet;
Rash;
Shift of body fat to stomach and upper back;
Stomach pain;
Taste disorders;
Vomiting.

Cautions / Warnings:

Not recommended in people with:
Allergic reactions to this medication or any of its ingredients;
A history of taking astemizole, cisapride, delavirdine, an ergot derivative (eg, ergotamine), eletriptan, erythromycin, certain HMG-CoA reductase inhibitors;
Diabetes;
Hemophilia or other bleeding disorders;
High cholesterol or triglyceride levels;
High blood sugar;
Liver disease;
Skin rashes;
Kidney disorders.

It is also not advisable in pregnant women; those that are planning on becoming pregnant and nursing mothers.

Drug Interactions:
Carbamazepine, dexamethasone, methadone, non-nucleoside reverse transcriptase inhibitors (NNRTIs) (eg, efavirenz, nevirapine), oral contraceptives (birth control pills), phenobarbital, phenytoin, rifampin, saquinavir, or St. John's wort;
HIV protease inhibitors (eg, indinavir, ritonavir);
Astemizole, certain HMG-CoA reductase inhibitors (eg, lovastatin, simvastatin), cisapride, eletriptan, ergot derivatives (eg, ergotamine), erythromycin, midazolam, pimozide, quinazolines (eg, alfuzosin), sumatriptan, terfenadine, or triazolam;
Aldosterone blockers (eg, eplerenone), antiarrhythmics (eg, amiodarone, bepridil, flecainide, lidocaine, propafenone, quinidine), azole antifungals (eg, itraconazole, ketoconazole), benzodiazepines (eg, alprazolam), calcium channel blockers (eg, diltiazem, amlodipine), fluoxetine, fluticasone, immunosuppressants (eg, cyclosporine, tacrolimus);
Delavirdine;
Anticoagulants (eg, warfarin).

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About Amprenavir

The generic name of this medication is amprenavir and the brand name is Agenerase. The active ingredient of this medication is Amprenavir. Agenerase capsules is manufactured by Glaxo SmithKline Pharmaceuticals. This medication is used in treating HIV infection and it is administered in combination with other drugs.

About Amprenavir

Amprenavir (Agenerase, GlaxoSmithKline) is a protease inhibitor used to treat HIV infection. It was approved by the Food and Drug Administration on April 15, 1999 for twice-a-day dosing instead of needing to be taken every eight hours. The convenient dosing came at a price, as the dose required is 1,200mg delivered in eight very large gel capsules. Production of amprenavir was discontinued by the manufacturer December 31, 2004; however, a prodrug version (fosamprenavir) is available.

Source: Wikipedia

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