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7.1  Effectiveness
6.7  Side Effects
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RateADrug users have reported 11 Simponi side effects and 6 Simponi benefits.

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User Comments and videos for Simponi
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03 Feb 2016 Pain is less with simponi but I have started back being sick on stomach,depressed and weak feeling. Life is useless. I was on Simponi before and had same thing. Did not relate nausea to simponi then.
   —Posted by Anonymous
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14 Aug 2015 I am blessed to find a medication that will control my colitis but do have issues with a few side effects. I have a real down time about 4-5 days after my injection. I get very withdrawn and somewhat depressed and to myself.I get very tired and just try to push through but some months are worse than others. I have also noticed my memory and focus seems to be getting worse. Other than that I am really happy with it.I know all medicines have side effects and I can deal with them to have a life.
   —Posted by Robin Jones
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19 Oct 2012 Have been on Simponi since late July(3 injections) . Was pain-free within 2 days. Was also taking leflunimide and small doses of prednisone. Worked well until about 3 days before last injection, pain and stiffness returned. Again pain-free within 24 hours after injection. Worked well for about 3 weeks then faded fast, RA came back with a vengeance. Anxious to get relief with next injection!
   —Posted by Kibrown
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30 Sep 2012 I stopped taking Simponi because my new ins wouldnt cover it. I was put in humira which was a lot better.
   —Posted by Cahuliva
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29 Sep 2012 I don't feel simponi helps me as much as remicade did, but it is better than humira. I was also not taking anything for my AS for about 8 months and when I started the simponi I was in a horrible flare up. I've only been on simponi for 2 months now so it may need more time to reach the full potential.
   —Posted by Sharel d
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