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Tamoxifen Citrate

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5.8

2.5 Effectiveness

6.1 Side Effects

2.9 Holistic Benefits

RateADrug users have reported 11 Tamoxifen Citrate side effects and 2 Tamoxifen Citrate benefits.

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Treatment Information

Description | Uses & Side Effects | Warnings

Tamoxifen is a nonsteroidal antiestrogen, which is administered orally and is part of a set of medications referred to as SERMs or selective estrogen receptor modulators. These have both estrogenic and anti-estrogenic effects. Tamoxifen has anti-estrogenic effects on the breasts and has estrogen-like effects on bones, working to strengthen them.

The inactive ingredients of tamoxifen citrat include carboxymethylcellulose calcium, magnesium stearate, mannitol and starch. Tamoxifen citrate is the active ingredient and it is available in 10 mg and 20 mg tablets.

Tamoxifen is used in the treatment of metastatic breast cancer in women and men and as a form of adjuvant treatment of breast cancer. It also decreases the risk of breast cancer in high risk women who are at a higher risk of developing breast cancer.

Common Uses:

Treatment of metastatic breast cancer in both women and men.
Alternative treatment to surgical removal of both ovaries and radiation treatment of the ovaries in postmenopausal women with metastatic breast cancer.
Minimizes the risk of ductal carcinoma in situ (DCIS)in women, post surgery and/or radiation treatment.
Decreases the occurrance of breast cancer in women that are at a high risk of developing carcinoma of the breast.

Off Label Uses:

Treatment of breast pain or mastalgia in women.

Side Effects:
Anemia.
Back pain.
Bone pain.
Chest pain.
Depression.
Diarrhea.
Difficulty breathing.
Fatigue.
Hair loss.
Headaches.
Heartburn or indigestion.
High blood pressure.
High cholesterol.
Hot flashes.
Infections.
Irregular menstrual periods.
Lack of sleep or insomnia.
Mood swings.
Muscle pain.
Nausea.
Osteoporosis.
Ovarian cysts.
Skin changes.
Vaginal bleeding.
Vaginal discharge.
Water retention.
Weight loss.

Cautions / Warnings:

Blood clots.
Strokes.
Uterine cancer.
Not recommended for people with bone metastases as it increases the calcium levels.
Not recommended for women with uterine cancer and ovarian conditions like ovarian cysts, fibroids, and endometriosis.
Not recommended in people with existing liver conditions like liver cancer, cirrhosis, and hepatitis.
Eye conditions include cataracts, vision changes, and other problems.
Not recommended for pregnant women and nursing mothers.

Drug Interactions:
Aminoglutethimide or Cytadren.
Anastrozole or Arimidex.
Anticonvulsants like carbamazepines like Epitol, Equetro, Tegretol, and Tegretol XR.
Bromocriptine or Parlodel.
Fosphenytoin or Cerebyx.
Oxcarbazepine or Trileptal.
Phenobarbital or Luminal.
Phenytoin or Dilantin.
Phenytek.
Primidone or Mysoline.
Chemotherapy medications like, estrogens or other hormone replacement therapy.
Letrozole or Femara.
Oral contraceptives or birth control pills.
Rifamycin antibiotics, including rifabutin or Mycobutin, rifapentine or Priftin.
Warfarin or Coumadin.
Jantoven.

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About Tamoxifen Citrate

Tamoxifen is a nonsteroidal antiestrogen, which is administered orally and is part of a set of medications referred to as SERMs or selective estrogen receptor modulators. These have both estrogenic and anti-estrogenic effects. Tamoxifen has anti-estrogenic effects on the breasts and has estrogen-like effects on bones, working to strengthen them. The inactive ingredients of tamoxifen citrat include carboxymethylcellulose calcium, magnesium stearate, mannitol and starch. Tamoxifen citrate is the active ingredient and it is available in 10 mg and 20 mg tablets. Tamoxifen is used in the treatment of metastatic breast cancer in women and men and as a form of adjuvant treatment of breast cancer. It also decreases the risk of breast cancer in high risk women who are at a higher risk of developing breast cancer.

Source: Wikipedia

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