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Triclabendazole

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About Triclabendazole
The commonly used brand name of this medication is Fasinex. It is not commercially available in the U.S. and Canada. It functions as an anthelmintic (systemic) medication. It is used in veterinary practice for the treatment of fascioliasis. Fascioliasis is a condition of herbivorous animals like sheep, cattle, and goats, which are the normal hosts. Humans are accidental hosts. This condition occurs due to consumption of uncooked, and usually unwashed, aquatic vegetables containing parasitic larvae.
About Triclabendazole
Triclabendazole (commercial name Fasinex) is a member of the Benzimidazole family of anthelmintics. The benzimidazole drugs share a common molecular structure, triclabendazole being the exception in having a chlorinated benzene ring but no carbamate group.

Triclabendazole displays high efficacy against both immature and adult liver fluke.

It is generally accepted that benzimidazoles like triclabendazole bind to beta-tubulin and prevent the polymerisation of the microtubules of which they are part.

Source: Wikipedia




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