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1.8  Effectiveness
7.7  Side Effects
4.7  Holistic Benefits

RateADrug users have reported 13 Agomelatine side effects and 5 Agomelatine benefits.

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This comedian is self-proclaimed to be a "weird, serious person," and has been battling clinical depression since childhood.


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Late night talk show host Larry King had a bout with depression after having heart surgery in 1987.

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22 Jul 2021 love this valdoxan it has changed my life from some one who hardly had any will to achieve anything any more due to severe depression and anxiety and so tired all the time, now i cant wait to get up every morning, I love doing projects at home,also started to send clothes and food to a village in Fiji who are suffering because of Covid19 no tourist no income for the majority of the people in the Village,so life now has excitement and meaning after going off lexapro and starting Valdoxan.
   —Posted by andy 54
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13 Apr 2018 The only anti-depressant that has helped insomnia and depression. I am 70 and have suffered depression since childhood. It has completely fixed my lifelong insomnia, whereas SSRIs worsened insomnia and caused numerous side effects and terrible withdrawal symptoms. I have been able to completely cease Xanax and have reduced Zoloft to 100mg. I am tapering off Zoloft with no withdrawal effects so far. GP optimistic I can get off Zoloft completely as it stopped working years ago but could not stop, even with tapering because of withdrawal. Valdoxan maynot work fir everyone, but no anti-depressant does but it certainly works for me.
   —Posted by Lily
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30 Sep 2017 6 weeks after starting felt much better mentally but got unusual symptoms. Joints in feet and knees became stiff and made movement painful and difficult. Around 3 months after starting I got a severe pain in my left side. Medical tests showed enlarged lymph nodes in my stomach. Further tests revealed more enlarged lymph nodes in spleen, neck and activation of bone marrow. Have been diagnosed with sarcoidosis.
   —Posted by Leigh
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27 Jul 2017 Hasn't been the greatest experience so far but not the worst. I'm a mum of a toddler and I barely sleep as it is so it's hard sometimes. I've had depression and anxiety for almost 6 years now. I also suffered from post natal depression too after having my daughter. I also have ADD and I'm on dexamphetimines for it. I'm having trouble controlling my moods since stopping my last antidepressant (lexapro) and coming into this one. I'm slowly getting there. Hopefully it'll help even more soon and I won't feel so hopeless. Not to mention, I've also had suicidal thoughts since stopping last medication.
   —Posted by Anonymous
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27 Jul 2017 I am taking Valdoxan for 5 years now. It helps me with sleep and as a result my overall mood is much better. It took me about four months at the beginning to realize changes. Keep going and hope it will help to you, too.
   —Posted by Anonymous
14 Jul 2015 I was on 25mg for a year. I was fine. Doctor increased to 50mg a week ago and my head is about to explode. Headaches and migraines are driving me insane! Trying to figure out if that's momentary or not.
   —Posted by Celso
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