Myo-Inositol was classified as a member of the vitamin B complex (often referred to as vitamin B8), but was found to be synthesized by the human body (thus, declassifying it as a vitamin[citation needed]). It should be noted, however, that substances such as niacin and choline can also be synthesized in the body, but are not made in amounts considered adequate for good health, and are classified as essential nutrients. Inositol as the basis for a number of signaling and secondary messenger molecules, is involved in a number of biological processes, including: * Insulin signal transduction * Cytoskeleton assembly * Nerve guidance (Epsin) * Intracellular calcium (Ca2+) concentration control * Cell membrane potential maintenance * Serotonin activity modulation * Breakdown of fats and reducing blood cholesterol * Gene expression