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Cymbalta

User Ratings
Out of 10
Satisfaction
5.2
3.7  Effectiveness
7.1  Side Effects
5.3  Holistic Benefits

RateADrug users have reported 14 Cymbalta side effects and 5 Cymbalta benefits.

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Treatment Information
The generic name of this medication is duloxetine and brand name is Cymbalta.
The active ingredients of this medication are Duloxetine, Serotonin/Norepinephrine Reuptake Inhibitor and Antidepressant.
Cymbalta is manufactured by Eli Lilly and Company.
Mainly used to treat major depressive disorder and general anxiety disorder.
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Mary Kate Olsen

Mary Kate Olsen has struggled with depression, ADD and the eating disorder anorexia nervosa.

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Owen Wilson

Owen Wilson has struggled with depression for years, and despite taking anti-depressants tried to commit suicide in 2007.

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Sheryl Crow

When Crow suffered a bad stretch of depression in 2003, the musician began an exercise routine and took Prozac to assist in her recovery.

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Jim Carrey

This comedian is self-proclaimed to be a "weird, serious person," and has been battling clinical depression since childhood.

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Larry King

Late night talk show host Larry King had a bout with depression after having heart surgery in 1987.

How does your Treatment Compare?
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BrandsEffectivenessHolistic BenefitsSide
Effects
Number of Ratings
5.79 6.18 3.68 42 Get Info
5.39 5.71 4.64 54 Get Info
4.35 5.25 5.67 57 Get Info
4.16 5.01 5.57 49 Get Info
3.28 4.76 5.86 60 Get Info
View All About these Scores Get Your Score
Effectiveness of Cymbalta by Condition
Click on a condition to view RateADrug.com users ratings
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Effectiveness on "Depression"
Bar Chart
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Not at all Mildly Moderately Very Extremely
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Reported Changes in Health and Well-Being
Since taking Cymbalta, RateADrug survey participants noticed these changes in their health:
Effect on:Much WorseWorseNo ChangeBetterMuch Better
Appetite 7.5% 29.1% 45.5% 11.2% 6.7%
Balance/Equilibrium 5.3% 20.5% 63.6% 6.1% 4.5%
Blood Pressure 5.3% 13% 74% 6.9% 0.8%
Breathing 1.5% 10.8% 77.7% 9.2% 0.8%
Confidence 11.6% 10.9% 37.7% 26.1% 13.8%
Coordination/Motor Skills 6.7% 20.9% 53.7% 14.2% 4.5%
Digestion 11% 18.1% 64.6% 4.7% 1.6%
Emotional Well-being 16.8% 18.9% 14.7% 28.7% 21%
Energy 17.1% 26.4% 20% 27.9% 8.6%
Eyesight 5.3% 17.6% 69.5% 5.3% 2.3%
Memory 13.5% 18% 45.9% 11.3% 11.3%
Mental Clarity 17.8% 18.5% 28.1% 23.7% 11.9%
Pain 5.3% 11.5% 58% 20.6% 4.6%
Patience 13.3% 17.8% 27.4% 30.4% 11.1%
Sexual Health 17.6% 15.4% 50.7% 11.8% 4.4%
Skin Complexion 4.8% 11.9% 81% 1.6% 0.8%
Sleep 11.3% 29.6% 26.8% 26.1% 6.3%
Stress Level 11.9% 14.9% 31.3% 25.4% 16.4%
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Commonly Reported Cymbalta Side Effects
RateADrug survey participants experienced these commonly reported side effects:
Effect on:NoneMildModerateStrongSevere
Swelling 81.2% 6.2% 6.2% 0% 6.2%
Cold Symptoms 82.9% 2.9% 8.6% 2.9% 2.9%
Appetite Loss 43.8% 18.8% 37.5% 0% 0%
Headache 49.2% 19.7% 17.4% 3.8% 9.8%
Difficulty Urinating 81% 6.3% 6.3% 6.3% 0%
Gas 80% 14.3% 2.9% 0% 2.9%
Fatigue 42.2% 13.3% 16.3% 14.8% 13.3%
Depression 47.4% 18.4% 13.2% 15.8% 5.3%
Sensitivity to Light 75% 11.1% 2.8% 8.3% 2.8%
Mood Swings 63.9% 11.1% 8.3% 5.6% 11.1%
Blurred Vision 61.1% 22.2% 2.8% 11.1% 2.8%
Breathing Difficulties 88.6% 2.9% 8.6% 0% 0%
Vomiting 70.6% 11.8% 11.8% 0% 5.9%
Sexual Dysfunction 66.2% 7.5% 7.5% 10% 8.8%
Stomach Ache 75% 11.1% 2.8% 5.6% 5.6%
Confusion 66.7% 13.9% 8.3% 8.3% 2.8%
Fever 88.6% 5.7% 5.7% 0% 0%
High Blood Pressure 66.7% 6.7% 0% 13.3% 13.3%
Irregular Heartbeat 75% 13.9% 2.8% 8.3% 0%
Constipation 43.2% 17.9% 18.9% 10.5% 9.5%
Change in Sex Drive 48.4% 7.8% 18% 11.7% 14.1%
Anxiety 50.4% 20.9% 16.5% 7% 5.2%
Drowsiness 42.9% 22.9% 14.3% 10% 10%
Nausea 63.4% 17.9% 7.1% 6.2% 5.4%
Dry Mouth 39.4% 26.5% 18.2% 10.6% 5.3%
Rapid Heartbeat 50% 50% 0% 0% 0%
Dizziness 50.8% 22% 11.4% 9.8% 6.1%
Sweating 41.5% 17.1% 12.2% 14.6% 14.6%
Abdominal Pain 69.6% 16.1% 7.1% 7.1% 0%
Change in Weight 42.9% 19% 19% 14.3% 4.8%
Tremors 66.7% 13.3% 20% 0% 0%
Erectile Dysfunction 89.7% 5.9% 1.5% 2.9% 0%
Bleeding 93.8% 0% 6.2% 0% 0%
Insomnia 46.9% 13.1% 17.7% 11.5% 10.8%
Relaxed / Calming Sensation 63.2% 14.7% 13.2% 7.4% 1.5%
Allergic Reaction 89.3% 3.3% 4.9% 1.6% 0.8%
Irritability / Impatience 52.9% 12.7% 13.7% 8.8% 11.8%
Muscle Cramping 69.4% 11.1% 11.1% 5.6% 2.8%
Diarrhea 84% 4% 7.2% 1.6% 3.2%
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Less Commonly Reported Cymbalta Side Effects
RateADrug survey participants experienced less commonly reported side effects:
Effect on:NoneMildModerateStrongSevere
Reduced Libido 63.8% 5.2% 12.1% 10.3% 8.6%
Anxiety 0% 100% 0% 0% 0%
Increased Depression 68.4% 12.7% 10.1% 6.3% 2.5%
Suicidal Tendencies 74% 8.3% 7.3% 4.2% 6.2%
Rapid Heartbeat 71.4% 7.1% 21.4% 0% 0%
Vertigo 0% 0% 0% 100% 0%
Change in Sex Drive 0% 33.3% 0% 33.3% 33.3%
Feelings of Anger / Rage 69.2% 11.5% 0% 3.8% 15.4%
Slurred Speech 79.2% 8.3% 4.2% 0% 8.3%
Indigestion 76% 8% 0% 8% 8%
Tremors 47.6% 9.5% 19% 9.5% 14.3%
Relaxed / Calming Sensation 90% 0% 10% 0% 0%
Cough 81.2% 12.5% 6.2% 0% 0%
Nausea 50% 27.8% 0% 0% 22.2%
Seizures 94% 3.6% 2.4% 0% 0%
Change in Weight 43.2% 18.2% 20.5% 8% 10.2%
Impaired Thinking / Judgment 64% 16% 0% 4% 16%
Irritability / Impatience 58.3% 16.7% 25% 0% 0%
Confusion 52.6% 0% 21.1% 10.5% 15.8%
Double Vision 70.6% 5.9% 5.9% 0% 17.6%
Energy Loss 42.9% 14.3% 14.3% 14.3% 14.3%
Liver Damage 96.4% 2.4% 1.2% 0% 0%
Blurred Vision 64% 13.3% 16% 1.3% 5.3%
Slow Reflexes 69.2% 11.5% 7.7% 0% 11.5%
Acne 80% 6.7% 6.7% 0% 6.7%
Aggressive / Impulsive Behavior 66.7% 11.1% 3.7% 7.4% 11.1%
Fainting 87% 0% 4.3% 4.3% 4.3%
Ulcer 80% 20% 0% 0% 0%
Sexual Dysfunction 60% 30% 10% 0% 0%
Hallucinations 71.9% 6.2% 9.4% 6.2% 6.2%
Sweating 0% 20% 20% 20% 40%
Mouth Sores 75% 6.2% 18.8% 0% 0%
Alcohol cravings 85.6% 5.8% 2.9% 2.9% 2.9%
Gas 64.3% 7.1% 21.4% 7.1% 0%
Amnesia / Memory Loss 60% 8% 8% 8% 16%
Elevated Cholesterol Level 93.8% 0% 6.2% 0% 0%
Increased Urination 71.4% 0% 14.3% 14.3% 0%
Depression 63.2% 10.5% 0% 5.3% 21.1%
Disorientation 61.5% 11.5% 11.5% 7.7% 7.7%
Coordination / Balance Problems 57.1% 14.3% 9.5% 4.8% 14.3%
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Episodes since taking Cymbalta
Since taking Cymbalta Rate a Drug survey participants reported these episodes:
Auto Accident 3.1%
Blindness 0.5%
Fall 6.7%
Hallucination 2.6%
Hospitalization 7.2%
Seizure 1.5%
Stroke 0.5%
About these Results  
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User Comments about Cymbalta
04 Aug 2018 Cymbalta created a horrific experience for me. I stopped taking Cymbalta due to feeling constantly tired and fatigued. While taking Cymbalta I slept for 12 hours per night and was still tired. I was not experiencing depression, but extreme somnolence. I also had several nightmares each night and nighttime sweating while taking Cymbalta. Now that I am off of Cymbalta, I sleep 7-8 hours and feel energetic and in a better mood. I only have a nightmare every few weeks now and no sweating. Getting off of Cymbalta was excruciatingly painful. I experienced nausea, vomiting, headaches, fatigue, dizziness, brain zaps and vertigo for weeks. I gradually reduced my dose over several weeks to hopefully avoid withdrawal symptoms with no luck. My doctors never warned me about this medication. Eli Lilly claims that this drug only caused withdrawal symptoms in approximately 1 percent of the population, but it's actually over 50 percent if you read studies about this medication. Eli Lilly is deceptive and doesn't want people to get off of this medication. This is why the smallest dosage of Cymbalta manufactured is 20mg so tapering off this medication is very difficult. If I would have known about the side effects and withdrawal symptoms I would have NEVER taken Cymbalta.
   —Posted by Brianna
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02 Jun 2017 Disappointed; had to supplement with Cipralex. If I stop taking these drugs I get migraines lasting 10 to 14 hours. I am held rand some by these chemicals....
   —Posted by Anonymous
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08 Apr 2017 It's made a tremendous difference in the level of pain I perceive in my OA hip. Without it, I can't work. Will be having a total hip replacement this year, but this drug allowed me to delay that operation for a couple of years. Helped me with SAD and I don't get weepy over sappy movies and commercials. On the sexual side, it does make it more difficult to achieve orgasm but is easily compensated for by dosage timing, just don't try to have an orgasm within 8 hours of taking dose.
   —Posted by Dman
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11 Nov 2013 Problems with this drug are: overstimulation, feeling restless, involuntary clenching of teeth and jaw-clenching. Even small twitching of whole muscle groups like the shoulders. Cymbalta is kind of like a toned-down version of Prozac or Zoloft in that it doesn't have such a powerful stimulant/antidepressant profile. But it is nasty, you can tell from the side-effects that taking Cymbalta is not healthy for you. No way would I recommend being on Cymbalta if there is any better option available to you. Also even the 30 milligrams per day seems too strong.
   —Posted by Anonymous
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11 Nov 2013 Problems with this drug are: overstimulation, feeling restless, involuntary clenching of teeth and jaw-clenching. Even small twitching of whole muscle groups like the shoulders. Cymbalta is kind of like a toned-down version of Prozac or Zoloft in that it doesn't have such a powerful stimulant/antidepressant profile. But it is nasty, you can tell from the side-effects that taking Cymbalta is not healthy for you. No way would I recommend being on Cymbalta if there is any better option available to you.
   —Posted by JB
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